Isaiah 53:3 He is despised and rejected by men, A Man of sorrows and acquainted with grief. And we hid, as it were, our faces from Him; He was despised, and we did not esteem Him.
I Peter 4 1-4 “… 3 For we have spent enough of our past lifetime[b] in doing the will of the Gentiles—when we walked in lewdness, lusts, drunkenness, revelries, drinking parties, and abominable idolatries. 4 In regard to these, they think it strange that you do not run with them in the same flood of dissipation, speaking evil of you.”
Rejection and despise is common for a person who wants to follow the Lord whole-heartedly. The obedience to the Lord means the world will hate us, because we do not run along with their flow.
Our Lord who, being in the form of God, did not consider it robbery to be equal with God, but made Himself of no reputation, taking the form of a bondservant, and obeyed God the Father. He humbled Himself and became obedient to the point of death, even the death of the cross (Phil 2:6-8) .
His rejection by His own city did not deter Him to do what Father God wants Him to do. The Pharisees and elite council despised him, but that did not deter Him to perform what God the Father wants Him to do.
If our Lord went through this for His obedience, then we will also go through it. Two things that help us to get through this rejection phase; one is the presence of Holy Spirit who comforts us and the other is promise of God. With this we can run against a troop of unhappy family or friends or we can leap over the depression that weights our spirit down (Ps 18:29). We should not halt on the feelings of rejections, but by the power of the Holy Spirit, we should overcome it and continue in our race. Hold your shield of faith and reject all the arrows of the devil, which is coming at you through words or deeds. Stand for God in faith through obedience.